NanoConjugates

NanoConjugates are based on the variable domain of heavy chain only antibodies, linked to a reporter protein.
Their small size, defined labelling and reproducibility cause convincing benefits over standard antibody conjugates.

Standard Antibody Conjugate

~150 kDa

Mixture of polyclonal Antibodies
isolated from different immunized Animals:
unknown Composition and limited Reproducibility.

Acridinium as Reporter
Molecule for detection:
covers the whole Antibody
including Antigen Binding Sites.

Animal welfare unclear.

NanoConjugate

~50 kDa

Monoclonal (sequenced), controlled
Expression in E. coli:
very high Reproducibility guaranteed
and Binding Properties well
characterised.

Acridinium as Reporter
Molecule for detection:
covers only the linked
Reporter Protein.
Binding site stays fully accessibel.

No animals involved in Production Process.